Right in the center of Indiana is Indianapolis. This city boasts a little of everything you could want. The nicknames are pretty fun too. Whether you call it the Circle City, Naptown, or Indy, Indianapolis is a large city with lots to offer.
If you love arts, history, plenty of places to eat, and a vibrant nightlife, then Indy would be a great place to get away. A long weekend would be perfect to take in the sights and be able to see a little bit of everything.